For women who have a pattern of acne flares during menstruation, the use of spironolactone (Aldactone) combined with a birth control pill can be helpful. It has some anti-androgen effects and if taken approximately a week before menstruation, it can prevent acne flares.
Side Effects
Menstrual irregularity
Contraindications
Pregnancy
Renal insufficiency
Abnormal menstrual bleeding
Use of ACE inhibitors
Family history of ovarian cancer, breast cancer, or uterine cancer